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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity

Fig. 8

Exosome-induced VDAC1-Aβ complex formation is associated with ceramide Representative immunofluorescence images for PLA signals from VDAC1-Aβ complexes and ceramide in primary cultured neurons incubated with wild type mouse exosomes (a), 5xFAD mouse exosomes (b), or human AD patient serum-derived exosomes (c). Images in right panel are details at higher magnification (frames in left panel) with arrows pointing at PLA signals colocalized with ceramide

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