Fig. 5From: Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPGOverall survival (OS) of the atypical DIPG (aDIPG) cohort (a) compared with that of a contemporary typical DIPG (tDIPG) cohort. There was no significant difference in OS among the subgroups of patients with aDIPG, whereas the OS of patients with tDIPG was significantly worse (P < 0.00001). Histone H3 K27M mutation status was the major determinant of OS in diffuse aDIPG (b). There was no significant difference in OS between patients with H3 K27M–mutant aDIPG and tDIPGBack to article page