Fig. 4From: Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPGA t-distributed stochastic neighbor embedding (t-SNE) plot (a) and unsupervised cluster analysis (b) of methylome profiles of diffuse atypical DIPG (aDIPG). The methylation profiles of H3 K27M–mutant and IDH-mutant aDIPG formed distinct clusters with their respective typical and cerebral cortical counterpartsBack to article page