Skip to main content
Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures

Fig. 1

Cadaveric hippocampi reveal a spectrum of GCD in patients with epilepsy. (a, b, b’) Schematics explaining the coronal sectioning and structure of human hippocampus. (c-e) H&E-stained coronal sections of dentate gyrus (DG) from human cadavers, obtained from SCH archives: representative images demonstrate a typical structure (c) and compactness of the GC layer (c’) in a control human dentate gyrus (with no history of epilepsy/seizure), and GCD in certain seizure cases, ranging from focal “tram-track” (TT) phenotype (d-d”) to more diffused “disaggregated” (DA) form (e). Arrowhead indicates outer granular zone distal to hilus; open arrowhead indicates inner granular zone proximal to hilus; bv, blood vessel. Scalebars: 1 mm (c, d); 50 μm (c’, d’, d”, e)

Back to article page