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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism

Fig. 7

GABAergic synapses and N-tr-Aβ deposits in the neuropil in dup-15 with autism. The image shows an area rich in synapses with N-tr-Aβ deposits. The scale bar shows 20 μm. The numerical densities of Aβ-immunoreactive profiles of a diameter equal to at least 0.1 μm2 calculated per 100μm2 and numerical densities of GABAergic synapses colocalized with Aβ-immunoreactive profiles were significantly higher in autism and dup-15 groups than in control (*** p < 0.001)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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