Table 1 Patient demographics
From: Characterising cellular and molecular features of human peripheral nerve degeneration
Case Number | Age Range (Gender) | Mechanism of Injury | Intraoperative findings | Method from Fig. 1 | Reconstructive Nerve Procedure | Details of nerve liberated (denervated unless otherwise stated) | Sample used for histology or RT-qPCR? | Denervation Period (Days) |
|---|---|---|---|---|---|---|---|---|
1 | 20–30 (M) | Motorbike accident | Rupture | A | Right spinal accessory nerve transfer suprascapular | Distal stump of suprascapular | RT-qPCR | 4 |
2 | 30–40 (M) | Fall and laceration | Rupture and Laceration | B | Medical cutaneous nerve of arm autograft to ulnar | Distal stump of ulnar | RT-qPCR | 8 |
3 | 30–40 (M) | Motorbike accident | Neurotmesis | A | Spinal accessory nerve transfer to suprascapular | Distal Stump of suprascapular | RT-qPCR | 12 |
4 | 20–30 (F) | Trampoline accident (radius and ulnar mid-shaft fracture) | Neurotmesis | C | Sural nerve graft to ulnar | Sural (innervated) and distal stump of ulnar | RT-qPCR | 40 |
5 | 30–40 (M) | Motorbike accident | C5–7 Avulsion | A | Spinal accessory nerve transfer to suprascapular transfer and Double Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous and distal stump of suprascapular | RT-qPCR | 42 |
6 | 20–30 (M) | Motorbike accident | C5-T1 Avulsion | A | Right intercostal nerve transfer to long thoracic nerve | Distal stump of long thoracic nerve | RT-qPCR | 110 |
7 | 30–40 (M) | Glass Laceration | Laceration | N/A | Resection of left common peroneal nerve | Distal stump of common peroneal nerve | RT-qPCR | 116 |
8 | 20–30 (M) | Moped v Lampost | C5–8 Avulsion | A | Intercostal nerve transfer to radial nerve | Intercostal (innervated) and distal stump of radial nerve | RT-qPCR | 119 |
9 | 40–50 (M) | Motorcycle v car and bus | C5/6 Avulsion | A | Spinal accessory nerve transfer to suprascapular | Distal stump of suprascapular nerve | RT-qPCR | 119 |
10 | 20–30 (M) | Car v Tree | C5/6/7 Avulsion | A | Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous | RT-qPCR | 170 |
11 | 20–30 (M) | Motorbike accident | C5/6 Avulsion | A | Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous | RT-qPCR | 180 |
12 | 30–40 (M) | Fall and laceration | High ulnar nerve laceration | A | Anterior interosseous nerve transfer to ulnar nerve | Distal stump of ulnar nerve | RT-qPCR | 182 |
13 | 50–60 (M) | Mechanical fall | C5/6 Avulsion | A | Right anterior interosseous nerve transfer to ulnar | Distal stump of ulnar nerve | RT-qPCR | 270 |
14 | 50–60 (M) | Iatrogenic - left sided neck lymph node biopsy | Neurotmesis | A | Spinal accessory nerve transfer to suprascapular | Distal stump of suprascapular | RT-qPCR | 375 |
15 | 40–50 (M) | Road Traffic Accident | C5-T1 Avulsion | A | Spinal accessory nerve transfer to suprascapular | Distal stump of suprascapular | RT-qPCR | 478 |
16 | 40–50 (M) | Car v Lorry | Axonotmesis | A | C7 fascicle to spinal accessorynerve | Distal stump of spinal accessory | RT-qPCR and Histology | 540 |
17 | 20–30 (M) | Stab wound to the neck | C5/6 Neurotmesis | A | Oberlin’s nerve transfer | Distal stump of C6 | Histology | 3 |
18 | 20–30 (M) | Motorbike v Car | C5/6 Avulsion | A | Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous | Histology | 30 |
19 | 20–30 (M) | Motorbike v Truck | Axonotmesis | A | Double Oberlin’s nerve transfer | Distal stumps of biceps and brachialis branches of musculocutaneous | Histology | 42 |
20 | 50–60 (F) | Mechanical Fall | C4/5/6/7 Avulsion | A | Double Oberlin’s nerve transfer | Distal stumps of biceps and brachialis branches of musculocutaneous | Histology | 58 |
21 | 20–30 (M) | Motorbike v Tree | Axonotmesis | A | Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous | Histology | 107 |
22 | 20–30 (M) | Seizure whilst driving | Axonotmesis | A | Oberlin’s nerve transfer | Distal stump of biceps branch of musculocutaneous | Histology | 172 |
23 | 20–30 (M) | Road Traffic Accident | C5/6 Avulsion | C | Free functioning muscle transfer to restore elbow flexion | Distal stump of biceps branch of musculocutaneous | Histology | 4745 |
24 | 30–40 (M) | Road Traffic Accident | C5-C8 Avulsion | C | Free functioning muscle transfer to restore elbow flexion | Intercostal (innervated) | RT-qPCR | 6432 |
25 | 20–30 (M) | Stab wound the neck | Neurotmesis | A | Subclavian nerve transfer to spinal accessory nerve | Distal stump of spinal accessory | Histology | 62 |
26 | 20–30 (M) | Motorbike v Car | Axonotmesis | A | Nerve to long head of triceps nerve transfer to axillary nerve | Distal stump of axillary nerve | Histology | 294 |
27 | 30–40 (M) | Motorbike accident | C5/6 Avulsion | A | Double Oberlin’s nerve transfer | Distal stumps of biceps and brachialis branches of musculocutaneous | Histology | 115 |