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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Characterising cellular and molecular features of human peripheral nerve degeneration

Fig. 2

Immunohistochemical detection of neurons in healthy and denervated human nerves. ac represent nerve cross sections stained for neurofilament (brown) with haematoxylin and eosin stain. The black arrow in the micrograph represents positive neurofilament staining. In d and e the black dotted line represents the mean number of axons detected in healthy nerve samples (case number 4 and 8). The x-axis is Log (denervation time in days). a Healthy sural nerve. b Biceps branch of the musculocutaneous nerve denervated for 30 days. c Axillary nerve denervated for 294 days with deteriorated morphology. d A scatter plot to represent Log (axon count/mm2) against denervation time. e Nonparametric smoothing linear regression of the Log (axon count/mm2) against denervation time. Case numbers are attached to each data point for reference to Table 1 with descriptors of whether the sample was collected proximally or distally: m1 - Proximal part of the denervated stump of the biceps branch of musculocutaneous nerve. m2 - Distal part of the denervated stump of the biceps branch of musculocutaneous nerve. b1 - Proximal section of the denervated stump of the brachialis branch of musculocutaneous nerve. s1 - Denervated stump of suprascapular nerve. sa1 - Proximal section of the denervated stump of the spinal accessory nerve. sa2 - Distal section of the denervated stump of the spinal accessory nerve

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