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Table 3 Antibody titers obtained with immunization protocol 2

From: Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes

Mimotope

(n = number of rats)

Titer

Anti-rat AQP4

Titer

Anti-human AQP4

Considered antibody-positive according to cut-off criteria***

III-01 (n = 8)

20

0

 

∆

0

20

 
 

10

0

 
 

80

20

***

 

0

0

 
 

40

20

***

 

0

0

 
 

160

40

***

IV-38 (n = 4)

5

10

 
 

0

0

 
 

0

0

 
 

0

0

 

I-13 (n = 5)

0

0

 
 

320

80

***

 

160

0

***

 

40

10

***

 

0

0

 

I-04 (n = 5)

40

10

***

 

20

20

 
 

320

160

***

 

40

40

***

∆

320

80

***

IV-04 (n = 5)

80

10

***

 

0

0

 
 

160

0

***

 

160

40

***

 

10

0

 
  1. ***Titers considered positive when single values for anti-rat AQP4 or anti-human AQP4 > 20
  2. ∆ Serum used for staining of rat astrocytes (Supplementary information S6)