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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma

Fig. 3

ROC curves of the copy number differences between the three dPCR assays for the prediction of the EGFRvIII variant. The three ROC curves represent the identification of the best diagnostic test to identify EGFRvIII using the absolute copy number differences between EGFR2 and the other dPCR assays, namely, EGFR1, EGFR3 and mean (EGFR1 + EGFR3). The best predictive test was selected using the highest AUC (difference of EGFR3 and EGFR2) and the threshold of the copy number difference that maximizes the sensitivity and specificity (10.8)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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