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Table 3 Neuropathological assessments

From: Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease

 CA4/CA3Temporal
IDType% PrP stainGliosisVacuo% PrP stainGliosisVacuo
sCJD
sCJD1VV237.262022.6421
sCJD2VV250.043156.0933
sCJD3VV220.152013.6521
sCJD4VV249.703228.9022
sCJD5VV232.072043.6310
sCJD6VV239.312046.1723
sCJD7VV242.612017.3120
sCJD8VV242.882160.2333
sCJD9VV237.421057.2721
sCJD10VV233.553314.9320
Mean (95% CI) 38.50 (32.19, 44.81)2.20 (1.75, 2.65)0.7 (−0.06, 1.46)36.08 (22.75, 49.41)2.10 (1.69, 2.51)1.4 (0.50, 2.30)
sCJD11MM12034.1333
sCJD12MM118.161053.8522
sCJD13MM10041.2622
sCJD14MM118.172161.8133
sCJD15MM120.252059.8933
sCJD16MM11040.8032
sCJD17MM121.990018.5011
sCJD18MM129.682158.4032
sCJD19MM121.482029.1722
sCJD20MM119.431057.8033
Mean (95% CI) 21.31 (17.63, 24.99)1.43 (0.70, 2.16)0.29 (−0.17, 0.74)48.49 (32.50, 64.48)2.43 (1.70, 3.16)2.29 (1.59, 2.98)
CtrlD
Ctrl11010
Ctrl21000
Ctrl30000
Ctrl 
Ctrl40000
Ctrl50010
Ctrl62010
  1. sCJD = sporadic Creutzfeldt-Jakob disease, CtrlD Diseased control, Ctrl Control, MM1 MM1 molecular subtype sCJD, VV2 VV2 molecular subtype sCJD, % PrP stain = % morphometric score of prion stain, Gliosis = score gliosis, Vacuo = score vacuolation