Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease

Table 1 Demographic overview, post-mortem delays and fixation times of included samples

ID	AOD	Sex	Molecular subtype	DD (months)	PMD (h)	FT (days)
sCJD
sCJD1	62	F	VV2	4	72	10
sCJD2	58	F	VV2	7	24	46
sCJD3	61	M	VV2	3	24	19
sCJD4	73	F	VV2	4	48	31
sCJD5	69	M	VV2	4	72	22
sCJD6	75	M	VV2	6	24	18
sCJD7	62	M	VV2	2	48	14
sCJD8	65	M	VV2	6	72	21
sCJD9	75	M	VV2	2	24	24
sCJD10	75	M	VV2	8	24	17
sCJD11	80	F	MM1	4	24	27
sCJD12	66	F	MM1	6	96	3
sCJD13	74	F	MM1	4	48	32
sCJD14	68	F	MM1	3	24	44
sCJD15	72	F	MM1	3	24	56
sCJD16	67	M	MM1	6	48	112
sCJD17	69	M	MM1	2	24	15
sCJD18	72	M	MM1	6	< 24	16
sCJD19	80	F	MM1	1.5	48	98
sCJD20	70	M	MM1	8	24	30
Ctrl_D
Ctrl1	67	F	–	–	24	31
Ctrl2	78	F	–	–	48	14
Ctrl3	81	F	–	–	24	37
Ctrl
Ctrl4	65	F	–	–	24	20
Ctrl5	73	F	–	–	48	22
Ctrl6	81	M	–	–	24	15

CJD Sporadic Creutzfeldt-Jakob disease, Ctrl_D Disease-control, Ctrl Control, AOD Age of death, PMD Post-mortem delay (hours), FT Fixation time (days), F Female, M Male, DD Disease duration in months

ISSN: 2051-5960