Fig. 5From: Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob diseaseNeuropathology correlates with complex I deficiency in the temporal cortex. Correlation plots of clinicopathological variables and MRC deficiency, exemplified by complex I (NDUFB8). Vacuolation and PrPsc-immunoreactivity correlate with gliosis in CA4/CA3 and temporal cortex (a). Vacuolation, gliosis and PrPsc-immunoreactivity correlate with mitochondrial complex I deficiency in the temporal cortex, (b) but not the hippocampal regions of CA4/CA3 (c)Back to article page