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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease

Fig. 5

Neuropathology correlates with complex I deficiency in the temporal cortex. Correlation plots of clinicopathological variables and MRC deficiency, exemplified by complex I (NDUFB8). Vacuolation and PrPsc-immunoreactivity correlate with gliosis in CA4/CA3 and temporal cortex (a). Vacuolation, gliosis and PrPsc-immunoreactivity correlate with mitochondrial complex I deficiency in the temporal cortex, (b) but not the hippocampal regions of CA4/CA3 (c)

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