Mouse Line | PrP. MoAβ/PS1 | PrP. HuAβ/PS1 | Tet. HuAβ | Tet. Bri42 | Bri42 Homo | PrP. APPsi | Tet. MoAβ |
---|---|---|---|---|---|---|---|
Amyloid pathology type | C | C > > D | C > D | D ≈ C | D > C | D > > C | D |
Age (mo) | 24 | 20 | 13 | 8 | 15 | 25 | 24 |
Number of LC/MS-MS | 2 | 3 | 4 | 4 | 3 | 3 | 3 |
Total # over-represented cytosolic proteins in SDS-insoluble fractions by pairwise comparison plus SAINT > 0.9 | 0 | 87 | 80 | 12 | 0 | 0 | 38 |
Avg. # SDS-insoluble Aβ spectra | 44 | 49 | 43 | 39 | 9 | 63 | 1 |
Avg. # SDS-insoluble Apoe spectra | 48 | 150 | 49 | 110 | 27 | 73 | 8 |
Avg. # SDS-insoluble Clu spectra | 6 | 33 | 23 | 16 | 5 | 10 | 4 |