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Table 4 Summary of data for APP/Aβ, Apoe, and Clusterin spectral counts in SDS-insoluble fractions

From: Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis

Mouse Line PrP. MoAβ/PS1 PrP. HuAβ/PS1 Tet. HuAβ Tet. Bri42 Bri42 Homo PrP. APPsi Tet. MoAβ
Amyloid pathology type C C > > D C > D D ≈ C D > C D > > C D
Age (mo) 24 20 13 8 15 25 24
Number of LC/MS-MS 2 3 4 4 3 3 3
Total # over-represented cytosolic proteins in SDS-insoluble fractions by pairwise comparison plus SAINT > 0.9 0 87 80 12 0 0 38
Avg. # SDS-insoluble Aβ spectra 44 49 43 39 9 63 1
Avg. # SDS-insoluble Apoe spectra 48 150 49 110 27 73 8
Avg. # SDS-insoluble Clu spectra 6 33 23 16 5 10 4