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Table 3 Functional Epigenetic Modules

From: Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients

FractionSeedP valueFunction
5mCFCER1G0.006Antibody-binding receptor
ELN0.011Elastic fiber formation
MDFI0.012Repression of myogenesis
TNF0.035Cytokine
DNMT3B0.038DNA methyltransferase
VAMP80.047Synaptic vesicle function
5hmCGRK20.004GPCR
SNRPB0.008Ribonucleoprotein
SSTR30.009Somatostatin receptor
ITGA40.019Lymphocyte homing receptor
ZBTB160.023Zinc finger transcription factor
  1. Summarization of identified functional epigenetic modules calculated for both the 5-methylcytosine (5mC) and the 5-hydroxymethylcytosine (5hmC) fractions. Seed: Center gene of module