Skip to main content

Advertisement

Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

Fig. 1

CA1 neurons in 6-mo Tg mice are enriched with tau oligomers. a Schematic of tau pathology progression in CA1 neurons of THY-Tau22 mice. b Representative images of sagittal CA1 sections from 6- and 12-mo Tg and Wt mice hippocampus (n = 3 for each mouse category). The sections were labeled with antibodies against pathological phospho-tau (pThr212), and tau oligomers (TOC1), respectively. The sections were analyzed by laser scanning confocal microscopy (z projection). Nuclei were visualized by DAPI staining. The scale bars represent 20 μm

Back to article page