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Table 1 Demographic details of cases used in study

From: Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer’s disease and aged brains: increased levels correlate with neuropathology

A. Demographic information of cases used for immunohistochemistry
 Gender (M:F)Mean age ± SDPMIAPOE4Plaque score±SEMTangle score±SEMBRAAK score
LP (n = 16)8/884.75 ± 6.962.93 ± 0.880% (0/32)2.54 ± 2.124.92 ± 2.33I-IV
HP (n = 15)7/885.62 ± 5.982.9 ± 0.6410.7% (3/28)10.49 ± 2.554.5 ± 1.93II-IV
AD (n = 14)6/880.64 ± 5.583.22 ± 0.9835.7% (10/28)13.33 ± 3.1512.46 ± 3.95V-VI
B. Demographic information of cases used for protein analysis
 Gender (F/M)Mean age ± SDPMIAPOE4Plaque scoreTangle scoreBRAAK score
LP (n = 12)6/685.91 ± 8.933.09 ± 1.024.5% (1/22)1.33 ± 1.935.43 ± 2.44I-IV
HP (n = 9)6/387.22 ± 8.222.72 ± 0.2812.5% (2/16)12.05 ± 1.585.38 ± 2.02II-IV
AD (n = 11)4/780.27 ± 3.823.79 ± 0.4736.7% (8/22)14.36 ± 0.6713.5 ± 1.96V-VI