Table 1 Demographic details of cases used in study
A. Demographic information of cases used for immunohistochemistry | |||||||
Gender (M:F) | Mean age ± SD | PMI | APOE4 | Plaque score±SEM | Tangle score±SEM | BRAAK score | |
LP (n = 16) | 8/8 | 84.75 ± 6.96 | 2.93 ± 0.88 | 0% (0/32) | 2.54 ± 2.12 | 4.92 ± 2.33 | I-IV |
HP (n = 15) | 7/8 | 85.62 ± 5.98 | 2.9 ± 0.64 | 10.7% (3/28) | 10.49 ± 2.55 | 4.5 ± 1.93 | II-IV |
AD (n = 14) | 6/8 | 80.64 ± 5.58 | 3.22 ± 0.98 | 35.7% (10/28) | 13.33 ± 3.15 | 12.46 ± 3.95 | V-VI |
B. Demographic information of cases used for protein analysis | |||||||
Gender (F/M) | Mean age ± SD | PMI | APOE4 | Plaque score | Tangle score | BRAAK score | |
LP (n = 12) | 6/6 | 85.91 ± 8.93 | 3.09 ± 1.02 | 4.5% (1/22) | 1.33 ± 1.93 | 5.43 ± 2.44 | I-IV |
HP (n = 9) | 6/3 | 87.22 ± 8.22 | 2.72 ± 0.28 | 12.5% (2/16) | 12.05 ± 1.58 | 5.38 ± 2.02 | II-IV |
AD (n = 11) | 4/7 | 80.27 ± 3.82 | 3.79 ± 0.47 | 36.7% (8/22) | 14.36 ± 0.67 | 13.5 ± 1.96 | V-VI |