Fig. 4

Quantitation of AT8-positive neurons in the MTL across CTE stages II, III, and IV. a-d Box plots show results from stereological quantitative measures of AT8-positive neurons with NFT (a) or puncta (b), as well as neurite clusters (c) and dystrophic neurites (d) across CTE stage II (green), stage III (red), and stage IV (blue). Statistical significance was determined using Kruskal-Wallis, Dunn post-hoc with a Bonferroni correction. * p < 0.05, ** p < 0.01