Fig. 1

IDH1 mutant LGGs exhibit differential chromatin accessibility. a Comparison of peaks called from pseudo-bulk snATAC-seq data (black) and bulk ATAC-seq on TCGA LGG data (green), b Density of read distribution for all samples around transcription start sites (TSS), c Distribution of the number of reads on all chromosomes for each sample, d Proportion of peaks that fall within each annotation genome class for each sample, e Gene set enrichment analysis for the enhancer regions of IDHmut-codel (left) and IDHmut-noncodel (right) samples