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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Regulation of microglial TMEM119 and P2RY12 immunoreactivity in multiple sclerosis white and grey matter lesions is dependent on their inflammatory environment

Fig. 6

Graphs of TMEM119 and P2RY12 mRNA levels in cultured primary human microglia derived from WM enriched areas or GM enriched areas treated with IFNγ+LPS or with IL-4 compared to untreated WM microglia. mRNA levels from GM derived cells are represented in the grey-coloured box. Data are presented as individual patient-derived microglia measurements and means (bars). N = 10 for all WM-derived microglia conditions, N = 7 for IL-4 treated GM-derived microglia N = 8 for IFNγ+LPS treated GM-derived microglia and N = 9 for untreated GM-derived microglia. * = p < 0.05

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Acta Neuropathologica Communications

ISSN: 2051-5960

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