Table 1 Individual case information. Cases were recoded according to their PHF1% load in hippocampus into their respective NFT score (“-“≤ 0.01%; 0.01%< “+” ≤1%;”++” > 1%). Hipp = Hippocampus. BG = Basal Ganglia. TCx = Temporal Cortex. ADRC = Alzheimer’s disease related changes
ID | Diagnosis | ABC score | Sex | Age | NFT score | Region |
|---|---|---|---|---|---|---|
High NFT 1 | AD | A3,B3,C3 | M | 89 | ++ | Hipp |
High NFT 2 | AD | A3,B3,C3 | F | 80 | ++ | Hipp + BG |
High NFT 3 | AD | A3,B3,C3 | F | 86 | ++ | Hipp |
High NFT 4 | AD | A3,B3,C3 | F | 98 | ++ | Hipp |
High NFT 5 | AD | A3,B3,C3 | F | 98 | ++ | Hipp |
High NFT 6 | AD | A3,B3,C3 | F | 85 | ++ | Hipp |
High NFT 7 | AD | A3,B3,C3 | F | 81 | ++ | Hipp |
High NFT 8 | AD | A3,B3,C3 | F | 92 | ++ | Hipp |
High NFT 9 | AD | A3,B3,C3 | F | 90 | ++ | Hipp |
High NFT 10 | AD | A3,B3,C3 | F | 71 | ++ | Hipp |
High NFT 11 | AD | A3,B3,C3 | M | 74 | ++ | Hipp + BG |
High NFT 12 | AD | A3,B3,C3 | F | 88 | ++ | Hipp |
High NFT 13 | AD | A3,B3,C3 | M | 79 | ++ | Hipp + BG |
High NFT 14 | AD | A3,B3,C3 | F | 83 | ++ | Hipp |
High NFT 15 | AD (early onset) | A3,B3,C3 | M | 69 | ++ | Hipp |
High NFT 16 | AD (early onset) | A3,B3,C3 | M | 63 | ++ | Hipp |
High NFT 17 | AD (early onset) | A3,B3,C3 | M | 63 | ++ | Hipp |
High NFT 18 | AD (early onset) | A3,B3,C3 | F | 60 | ++ | Hipp |
High NFT 19 | AD (early onset) | A3,B3,C3 | M | 62 | ++ | Hipp |
High NFT 20 | AD (early onset) | A3,B3,C3 | F | 55 | ++ | Hipp |
High NFT 21 | AD | A2,B2,C2 | M | 84 | ++ | Hipp |
Moderate NFT 1 | AD | A2,B3,C2 | M | 94 | + | Hipp |
Moderate NFT 2 | AD | A3,B3,C3 | F | 76 | + | Hipp |
Moderate NFT 3 | AD | A3,B3,C3 | M | 69 | + | Hipp |
Moderate NFT 4 | AD | A3,B3,C3 | M | 75 | + | Hipp |
Moderate NFT 5 | AD | A3,B3,C3 | F | 89 | + | Hipp |
Moderate NFT 6 | MCI | A1,B2,C1 | F | 97 | + | Hipp |
Moderate NFT 7 | MCI | A1,B2,C1 | F | 85 | + | Hipp |
Moderate NFT 8 | MCI | A2,B2,C2 | M | 84 | + | Hipp |
Moderate NFT 9 | AD | A2,B2,C2 | F | 84 | + | Hipp |
Moderate NFT 10 | MCI | A1,B1,C0 | F | 84 | + | Hipp |
Moderate NFT 11 | MCI | A1,B1,C1 | M | 79 | + | Hipp |
Moderate NFT 12 | MCI | A1,B1,C1 | M | 90 | + | Hipp |
Moderate NFT 13 | MCI | A1,B1,C1 | M | 74 | + | Hipp |
Moderate NFT 14 | MCI | A1,B1,C0 | M | 95 | + | Hipp |
Moderate NFT 15 | Normal | A1,B1,C0 | M | 77 | + | Hipp |
Moderate NFT 16 | MCI | A0,B1,C0 | M | 88 | + | Hipp |
Moderate NFT 17 | Vascular Dementia | A1,B1,C0 | F | 89 | + | Hipp |
Moderate NFT 18 | Normal | A1,B1,C0 | M | 69 | + | Hipp |
Moderate NFT 19 | Normal | A0,B1,C0 | F | 56 | + | Hipp |
Moderate NFT 20 | Normal | A0,B1,C0 | F | 59 | + | Hipp |
Moderate NFT 21 | Normal | A0,B1,C0 | M | 59 | + | Hipp |
Moderate NFT 22 | Normal | A1,B1,C0 | F | 71 | + | Hipp |
Low/no NFT 1 | Normal | A0,B0,C0 | M | 77 | – | Hipp |
Low/no NFT 2 | Normal | A0,B0,C0 | F | 49 | – | Hipp |
Low/no NFT 3 | Normal | A1,B1,C0 | M | 63 | – | Hipp |
Low/no NFT 4 | Normal | A0,B0,C0 | F | 51 | – | Hipp |
Low/no NFT 5 | Normal | A0,B0,C0 | M | 55 | – | Hipp |
Low/no NFT 6 | Normal | A0,B0,C0 | M | 57 | – | Hipp |
Low/no NFT 7 | Normal | A0,B0,C0 | M | 59 | – | Hipp |
Low/no NFT 8 | Normal | A0,B0,C0 | M | 57 | – | Hipp |
Low/no NFT 9 | Normal | A0,B0,C0 | M | 55 | – | Hipp |
Low/no NFT 10 | Normal | A0,B0,C0 | M | 54 | – | Hipp |
Low/no NFT 11 | Normal | A0,B0,C0 | M | 50 | – | Hipp |
Low/no NFT 12 | Normal | A1,B0,C0 | M | 59 | – | Hipp |
Low/no NFT 13 | Normal | A1,B1,C1 | M | 89 | – | Hipp |
Low/no NFT 14 | MCI | A2,B1,C1 | F | 89 | – | Hipp |
Low/no NFT 15 | MCI | A2,B1,C1 | M | 66 | – | Hipp |
Down Syndrome 1 | DS, AD | A3,B3,C3 | F | 58 | +++ | Hipp |
Down Syndrome 2 | DS, AD | A3,B3,C3 | F | 59 | +++ | Hipp |
Down Syndrome 3 | DS, AD | A3,B3,C3 | M | 54 | +++ | Hipp |
Down Syndrome 4 | DS, AD | A3,B3,C3 | M | 55 | +++ | Hipp |
Down Syndrome 5 | DS, AD | A3,B3,C3 | F | 54 | +++ | Hipp |
PART 1 | PART | A0,B2,C0 | M | 75 | + | Hipp |
PART 2 | PART | A0,B2,C0 | F | 86 | ++ | Hipp |
PART 3 | PART | A0,B2,C0 | F | 92 | + | Hipp |
PART 4 | PART | A0,B2,C0 | M | 94 | + | Hipp |
PART 5 | PART | A0,B2,C0 | F | 90 | ++ | Hipp |
PART6 | PART | A0,B2,C0 | M | 92 | ++ | Hipp |
CBD 1 | CBD | n/a | F | 73 | +++ | BG |
CBD 2 | CBD | n/a | M | 75 | +++ | BG |
CBD 3 | CBD | n/a | M | 79 | ++ | BG |
CBD 4 | CBD | n/a | F | 80 | + | BG |
CBD 5 | CBD | n/a | M | 68 | + | BG |
PSP 1 | PSP | n/a | M | 74 | + | BG |
PSP 2 | PSP | n/a | M | 71 | ++ | BG |
PSP 3 | PSP | n/a | M | 71 | + | BG |
PSP 4 | PSP | n/a | M | 71 | + | BG |
PSP 5 | PSP | n/a | F | 87 | + | BG |
PiD 1 | Pick’s Disease | n/a | M | 67 | + | Hipp |
PiD 2 | Pick’s Disease | n/a | M | 67 | ++ | Hipp |
PiD 3 | Pick’s Disease | n/a | F | 71 | +++ | Hipp |
PiD 4 | Picks Disease | n/a | F | 65 | +++ | Hipp |
HCHWA-D | Dutch amyloidosis | n/a | F | 54 | n/a | TCx |
FTLD-ADRC 1 | CBD with AD | A0,B1,C0 | M | 72 | n/a | Hipp |
FTLD-ADRC 2 | PSP with AD | A1,B3,C0 | F | 79 | n/a | Hipp |