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Table 1 Characteristics of post-mortem human brain samples

From: The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

Brain Region: Hippocampus (paraffin-embedded)
Braak StageNumber of SubjectsAge at DeathaGenderbAPOE4 StatuscCERAD ScoredDiagnosise
I679 ± 6.8M (1) F (5)+ (1), − (2)O(2), A(2), B(2)NDCNTRL
II685.7 ± 1.8M (1) F (5)+ (2), − (4)A(1), B(3), C(2)NDCNTRL
III682 ± 5.8M (5) F (1)+ (3), − (2)A(1), B(2), C(3)NDCNTRL
IV792.3 ± 3.3M (1) F (6)+ (2), − (5)CNDCNTRL (2), AD(5)
V482.3 ± 10.1M (0) F (4)+ (3), − (1)CAD
VI686 ± 6.8M (0) F (6)+ (4), − (2)CAD
Brain Region: Cortex (paraffin-embedded)
Braak StageNumber of SubjectsAge at DeathGenderAPOE4 StatusCERAD ScoreDiagnosis
I482.5 ± 9.3M (2) F (2)+ (0), − (4)A(1), B(2), C(1)NDCNTRL
II385.3 ± 0.5M (1) F (2)+ (1), − (2)A(1), B(3), C(2)NDCNTRL
III487 ± 3.7M (3) F (1)+ (2), − (2)A(1), B(2), C(3)NDCNTRL
IV689.3 ± 5.4M (2) F (4)+ (3), − (3)B(2), C(4)NDCNTRL (2), AD (4)
V384.3 ± 13.2M (0) F (3)+ (2), − (1)CAD
VI589.2 ± 3.4M (0) F (5)+ (4), − (1)CAD
Brain Region: Cortex (frozen)
Braak StageNumber of SubjectsAge at DeathGenderAPOE4 StatusCERAD ScoreDiagnosis
I – II488.7 ± 7.9M (0) F (4)+ (0), − (2)O(1), A(1), B(1), C(1)NDCNTRL
III – IV591.4 ± 2.9M (1) F (4)+ (1), − (2)O(1), B(2), C(2)NDCNTRL (3), AD (2)
V – VI575.2 ± 8.1M (2) F (3)+ (2), −(2)B(1), C(4)AD
  1. a Age at death is reported as mean ± standard deviation
  2. b M Male, F Female
  3. c APOE4 Status +: APOE3/4 or APOE4/4, −:APOE3/3, APOE3/2, APOE2/2. APOE4 status were not available for some subjects
  4. d CERAD Consortium to Establish a Registry for Alzheimer’s Disease
  5. e NDCNTRL Non-demented control, AD Alzheimer’s disease patient