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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson’s disease and multiple system atrophy

Fig. 4

Spectral analysis of HS-68- and pS129 α-syn antibody-positive inclusions in multiple system atrophy (MSA) and Parkinson’s disease (PD). a Mean emission spectra of HS-68 binding to pS129 α-syn positive deposits in MSA cases 6, 7 and 8 (coral, cerebellum) and PD cases 13, 15 and 16 (cyan, substantia nigra). b Plot of the ratio of emission intensity at wavelengths 485 and 573 nm for HS-68 when binding to inclusions in MSA (coral circles) and PD (cyan squares) that were also labelled with pS129 α-syn antibody. c Merging of the ratio values for all MSA (coral circles) and PD (cyan squares) cases shown in b. The results are expressed as means ± S.D. (n = 3) ****p < 0.0001

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Acta Neuropathologica Communications

ISSN: 2051-5960

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