Fig. 1
Comparison of the relationship of the Aβ phases (a), AβMTL phases (b), the A-scores (c), CAA stages (d) and CAA severities (e) with Aβ plaque loads for Aβ, AβN3pE, and AβpSer8-containig plaques in cohort 1, depicted by boxplot diagrams. a: The plaque-loads for Aβ (Spearman correlation analysis: r = 0.888) and AβN3pE (Spearman correlation analysis: r = 0.882) correlated better with the Aβ phases than that for AβpSer8-positive plaques (Spearman correlation analysis: r = 0.810). b-e: Likewise, the AβMTL phases (b), the A-scores (c), the CAA stage (d) and the CAA severity (e) correlated with the Aβ, AβN3pE, and AβpSer8 loads (r = 0.582–0.899; p < 0.001; for detailed statistical analysis see Additional file 1: Table S5a)