Table 1 Clinical parameters and molecular analyses of the tumors
Tumor number anaplastic astrocytomas | p53 | Ki67 | age at first symptoms | TERT promoter | C-circles (arbitrary units) |
|---|---|---|---|---|---|
3570 | 5% | 7% | 56 | wt | 20 |
4080 | 50% | 10% | 56 | wt | 6 |
4140 | 50% | 70% | 28 | wt | 82 |
4827 | 60% | 5% | 32 | wt | 55 |
5595 | 30% | 12% | 54 | wt | 91 |
6637 | 80% | 10% | 33 | wt | 87 |
4185 | 40% | 15% | 33 | wt | 80 |
3552 | 70% | 10% | 32 | wt | 21 |
4644 | 60% | 5% | 66 | wt | 31 |
3635 | 3% | 15% | 43 | wt | 19 |
3843 | 90% | 10% | 29 | wt | 31 |
3091 | 80% | 7% | 68 | wt | 10 |
4126 | 50% | 15% | 61 | wt | 7 |
4975 | 50% | 7% | 55 | wt | 10 |
3240 | 5% | 15% | NA | wt | 170 |
3402 | negative | 3% | 38 | wt | 1 |
4031 | 50% | 10% | 47 | wt | 31 |
4878 | negative | 15% | 24 | wt | 103 |
5815 | negative | 12% | 45 | wt | 14 |
3462 | 60% | 10% | 40 | wt | 60 |
4951 | 60% | 10% | 43 | wt | 11 |
5261 | 60% | 5% | 38 | wt | 59 |
5489 | 10% | 30% | 48 | C250T | 69 |
5546 | 80% | 10% | 27 | wt | 99 |
5841 | 60% | 10% | 58 | wt | 34 |
5895 | 100% | 5% | 51 | wt | 19 |
6013 | 60% | 6% | 33 | wt | 16 |
6095 | negative | 8% | NA | wt | 56 |
6658 | 60% | 12% | 33 | wt | 3 |
3558 | 100% | 20% | 39 | wt | 22 |
4056 | 50% | 15% | 29 | wt | 5 |
4289 | 90% | 10% | 28 | wt | 24 |
4572 | 90% | 8% | 42 | wt | 49 |
4840 | 75% | 8% | 34 | wt | 61 |
5238 | 80% | 8% | 55 | wt | 21 |
5744 | 50% | 12% | 34 | wt | 83 |
5987 | 80% | 15% | 35 | wt | 90 |
5443 | 80% | 12% | 61 | wt | 12 |
5448 | 50% | 12% | 29 | C228T | 37 |
5790 | 50% | 12% | 47 | wt | 18 |
5793 | 60% | 15% | 43 | wt | 35 |
5866 | 60% | 15% | 40 | wt | 91 |
6244 | 60% | 20% | 45 | wt | 22 |
6309 | 60% | 12% | 39 | wt | 102 |
4569 | 90% | 15% | 32 | C250T | 40 |
2944 | 70% | 10% | 57 | wt | 25 |
5022 | negative | 12% | 66 | wt | 24 |
5725 | 80% | 12% | 53 | wt | 12 |
6011 | 80% | 20% | 39 | wt | 46 |
5974 | 80% | 5% | 34 | wt | 16 |
5003 | 30% | 5% | 33 | C228T | 109 |
3684 | 25% | 7% | 33 | C228T | 1 |
4106 | negative | 10% | 31 | wt | 49 |
5593 | 60% | 10% | 34 | wt | 34 |
5594 | 80% | 11% | 59 | wt | 13 |
6654 | 60% | 8% | 52 | wt | 17 |
6742 | 40% | 4% | 48 | wt | 38 |
5510 | 35% | 20% | 28 | C228T | 45 |
5912 | 80% | 12% | 33 | wt | 0 |
5398 | 80% | 12% | 36 | wt | 21 |
Tumor number secondary GBM | p53 | Ki67 | patient age (years) | TERT promoter | C-circles |
3942 | 80% | 25% | 37 | wt | 6 |
2592 | 40% | 10% | 69 | wt | 41 |
3077 | 60% | 20% | 25 | wt | 16 |
3007 | 80% | 30% | 31 | wt | 82 |
3297 | 30% | 70% | 59 | wt | 77 |
4034 | 30% | 10% | 58 | wt | 7 |
4115 | 80% | 25% | 55 | wt | 101 |
3845 | 80% | 8% | 32 | wt | 32 |
3928 | negative | 30% | 41 | wt | 58 |
3933 | negative | 25% | 32 | wt | 88 |
3992 | 40% | 15% | 34 | wt | 20 |
3959 | 90% | 15% | 26 | wt | 13 |
3019 | 100% | 25% | 29 | wt | 136 |
2835 | 20% | 8% | 37 | wt | 52 |
3316 | 40% | 70% | 24 | wt | 68 |
2695 | 60% | 60% | 30 | wt | 38 |
3359 | 100% | 60% | 41 | wt | 10 |
3451 | 40% | 3% | 61 | wt | 40 |
4068 | 60% | 20% | NA | wt | 44 |
4082 | negative | 12% | 35 | wt | 35 |
4125 | 60% | 25% | 36 | wt | 6 |
4145 | 30% | 12% | 29 | wt | 29 |
4194 | 70% | 10% | 33 | wt | 34 |
4245 | 15% | 12% | 29 | wt | 24 |
4234 | 80% | 20% | 30 | wt | 22 |
4554 | 60% | 10% | 33 | wt | 24 |
4602 | 60% | 12% | 65 | C250T | 2 |
4711 | 20% | 10% | 57 | wt | 31 |
4706 | 80% | 40% | 39 | wt | 132 |
4707 | 90% | 30% | 40 | wt | 21 |
5007 | 60% | 12% | 53 | wt | 18 |
5014 | 100% | 30% | 62 | wt | 95 |
4918 | 60% | 15% | 36 | wt | 15 |
5067 | 95% | 15% | 33 | wt | 42 |
5246 | 80% | 5% | 36 | wt | 16 |
5248 | 80% | 30% | 44 | wt | 60 |
5160 | 60% | 12% | 67 | wt | 44 |
5137 | 50% | 50% | 32 | wt | 33 |
5152 | 95% | 12% | 72 | wt | 4 |
5169 | 60% | 20% | 36 | C228T | 16 |
5543 | 80% | 10% | 23 | wt | 12 |
5876 | 40% | 10% | 32 | wt | 0 |
5839 | 5% | 12% | 55 | wt | 26 |
5983 | negative | 25% | 43 | wt | 57 |