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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: The level of activity of the alternative lengthening of telomeres correlates with patient age in IDH-mutant ATRX-loss-of-expression anaplastic astrocytomas

Fig. 2

Correlation between the level of ALT activity, expressed as the percentage of radioactive signal with respect to the ALT signal recorded in genomic DNA from U2OS cells, designated to be 100 arbitrary units (AU), and patient age in anaplastic astrocytomas, AA (a, top and bottom left) and secondary glioblastomas multiform, GBM (b). Patient age was considered at the time of first surgery. a bottom right: According to statistical distribution, we arbitrarily defined two categories of anaplastic astrocytoma (AA) patients with C-circle score < or > 50 AU. This graphical representation also clearly shows the ALT intensity/patient age correlation

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