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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain

Fig. 2

N368-cleaved Tau fragments accelerate the aggregation of full-length Tau in vitro. A-B. Thioflavin S aggregation assays of mixtures between recombinant 2N4R wild-type full-length Tau and recombinant Tau1–368(a) or Tau256–368(b) fragments. The amount of Tau fragments in the reaction is indicated as molar fraction percentage respect to full-length Tau (mean, n = 3)

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