Fig. 2
The EPM test revealed ABET-induced anxiety-like behavior. a The top view of time spent in the open and closed arms of the EPM immediately after (Adolescent) mice received saline (top) or EtOH (bottom). Time spent on the EPM is shown in heat maps. b EPM heat maps for the testing about a month after (Adult) mice received saline (top) or EtOH (bottom). c Summary for percentage time spent in the open arms/(open + closed arms) for both Adolescent and Adult testing. Two-way ANOVA revealed a significant effect of the condition for time spent on the open arms [F1,33 = 4.66, p = 0.039]. There was no effect of the age [F1,33 = 0.01, p = 0.92], nor the condition and age interactions [F1,33 = 0.15, p = 0.70]. *, p < 0.05. d Summary for time spent on the closed arms for both Adolescent and Adult testing. Two-way ANOVA revealed a significant effect of the EtOH treatment for time spent on the closed arms [F1,33 = 10.01, p = 0.003]. There was no effect of the age (Adolescent vs. Adult) [F1,33 = 0.07, p = 0.8], nor the condition (Control vs. EtOH) and age interactions [F1,33 = 0.11, p = 0.75]. **, p < 0.01. The n number is provided within each bar