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Table 2 Correlation of motility-related markers with pan-Aβ, Aβ42 and ptau

From: Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study

  Iba1CFL1P2RY12CORO1A
pan-AβControlrs = 0.440*rs = 0.301rs = 0.443*rs = 0.055
ADrs = −0.055rs = 0.077rs = 0.219rs = 0.009
iADrs = −0.143rs = 0.011rs = 0.054rs = −0.029
Aβ42Controlrs = 0.691***rs = 0.459rs = 0.629***rs = 0.051
ADrs = −0.021rs = − 0.172rs = 0.078rs = − 0.158
iADrs = −0.464rs = −0.575rs = 0.171rs = 0.464
ptauControlrs = −0.113rs = −0.165rs = 0.017rs = 0.-173
ADrs = −0.239rs = −0.043rs = − 0.249rs = − 0.019
iADrs = −0.709rs = − 0.118rs = 0.191rs = 0.036
  1. rs Spearman’s rank correlation, *P < 0.05; *** P < 0.001, significant P values are in italic
  2. CFL1 cofilin 1, CORO1A coronin-1A
  3. Control neurologically/cognitively normal controls, AD Alzheimer’s disease cases, iAD immunised Alzheimer’s disease cases, ptau: phosphorylated tau