| | |
Number of affected fibers
|
---|
HE
|
Internalized nuclei
|
+
|
< 10%
|
++
|
10–30%
|
+++
|
> 30%
|
Fibrotic areas
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
Vacuoles
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
Ring Fibers
|
+
|
< 5%
|
++
|
5–10%
|
+++
|
> 10%
|
Necrosis
|
+
|
< 2%
|
++
|
2–5%
|
+++
|
> 5%
|
Regeneration
|
+
|
< 2%
|
++
|
2–5%
|
+++
|
> 5%
|
PAS
|
Augmented intensity
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
Positive vacuoles
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
IHC
|
SQSTM1/p62
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
EM
|
Intermyofibrillar glycogen accumulation
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
Autophagosomes
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
Autophagic structures
|
+
|
< 5%
|
++
|
5–30%
|
+++
|
> 30%
|
- For abbreviations see Table 3