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Table 1 Curve-fitting of DP data of Alzheimer’s disease mouse models

From: Tau- but not Aß -pathology enhances NMDAR-dependent depotentiation in AD-mouse models

Mice Mean τ rise (min) Mean ‘plateau level’ (% of baseline)
APPPS1–21 WT 19.7 ± 10 156 ± 11
APPPS1–21 TG 5.7 ± 1 135 ± 11
APPPS1–21 TG +SB216763 10 ± 4.5 124 ± 11
THY-tau 22 WT 21.3 ± 13 141 ± 7
THY-tau 22 TG 6.3 ± 1 118 ± 5
THY-tau 22 TG +SB216763 3.8 ± 1 116 ± 4