Table 1 Curve-fitting of DP data of Alzheimer’s disease mouse models
From: Tau- but not Aß -pathology enhances NMDAR-dependent depotentiation in AD-mouse models
Mice | Mean τ rise (min) | Mean ‘plateau level’ (% of baseline) |
|---|---|---|
APPPS1–21 WT | 19.7 ± 10 | 156 ± 11 |
APPPS1–21 TG | 5.7 ± 1 | 135 ± 11 |
APPPS1–21 TG +SB216763 | 10 ± 4.5 | 124 ± 11 |
THY-tau 22 WT | 21.3 ± 13 | 141 ± 7 |
THY-tau 22 TG | 6.3 ± 1 | 118 ± 5 |
THY-tau 22 TG +SB216763 | 3.8 ± 1 | 116 ± 4 |