Fig. 4
From: Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels
Pre-synaptic fraction shows stable protein levels between C9-WT and C9-KO mice. a Immunoblots from the pre-synaptic compartment (S3) from C9-WT and C9-KO mice (n = 2 mice per sample; n = 4 biological replicates per group). b Bar plots of mean S3 immunoblot band densities for each antibody probed in the S3 fraction. y-axis = relative density; error bars = standard deviation. Synaptophysin (Syp); TAR DNA Binding Protein 43 (TDP-43); Chromosome 9 open reading frame 72 (C9orf72); Smith-Magenis syndrome Chromosomal Region candidate gene 8 (Smcr8); Ras-related proteins Rab3a, Rab5, Rab11, Rab39b; Glutamate receptor 1 (GluR1); glutamate receptor 2 (GluR2); N-methyl-D-aspartic acid receptor 1 (NMDAR1)