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Table 2 Motor impairment of heterozygous mice transgenic for human mutant A53T α-synuclein following intracerebral injection of brain extracts from Parkinson’s disease (PD)

From: Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice

Human brain extract Age at death Mice injected Mice with motor impairment Survival (days) SD Survivors to 18 Mo Survivors with assembled α-synclein
(1) PD 76 3 0 3 2
(2) PD 83 4 4 288 79
(3) PD 92 3 1 265 2 1
(4) PD 68 3 1 335 2 1
(5) PD 74 4 1 3 1