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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson’s disease brain extracts in transgenic mice

Fig. 1

Survival of heterozygous mice transgenic for human mutant A53T α-synuclein following intracerebral injection of (a) cerebellar extracts from seven patients with multiple system atrophy (MSA) and (b) substantia nigra extracts from five patients with Parkinson’s disease (PD). Cerebellum from a neurologically unaffected individual served as control. Five MSA cases were of the parkinsonian type (MSA-P) and two cases of the cerebellar type (MSA-C). Assembled recombinant human α-synuclein was also injected (c)

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