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Table 3 Identified FMRpolyG proteotypic peptides

From: Composition of the Intranuclear Inclusions of Fragile X-associated Tremor/Ataxia Syndrome

Sequence

Modifications

Observed m/z

Charge

Theoretical Mass (Da)

Spectral Counts (MS/MS)

FMRpolyG-GFP (recombinant)

Native FXTAS Inclusions

Native FXTAS SUMO-IP

MEAPLPGGVR

Acetyl (+42)

534.78

2

1068.54

1

-

-

 

Acetyl (+42)

Oxidation (+16)

542.78

2

1084.54

-

1

-

EAPLPGGVR

 

448.25

2

895.50

-

1

-

SPPLGGGLPALAGLK

 

674.40

2

1347.80

3

1

2

SPPLGGGLPALAGLKR

 

501.97

3

1503.90

1

-

-

CGAPMALSTR

Carbamidomethyl (+57)

532.25

2

1063.50

1

-

-

 

Carbamidomethyl (+57)

Ammonia-loss (-17)

523.74

2

1046.50

1

-

-