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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Optimization of ultrastructural preservation of human brain for transmission electron microscopy after long post-mortem intervals

Fig. 6

Comparison of human brain samples with different PMIs prepared with standard embedding and hybrid freezing. Overview micrographs (3 × 3 montages) at low magnification (1500x) (a-d) samples with increasing PMI (case 1–4) prepared with standard embedding method; e-h Samples of the same area from the same cases processed with cryo-substitution cocktail I, hybrid freezing. Scale bars = 1 μm

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