From: Telomere alterations in neurofibromatosis type 1-associated solid tumors
Ā | Univariate | Multivariate | ||||||
---|---|---|---|---|---|---|---|---|
Ā | Death/Censor | Person-time (months) | HR | (95% CI) | P-value | HR | (95% CI) | P-value |
Age | 16/25 | 1482 | 1.01 | (0.98ā1.04) | 0.5 | 1.08 | (1.02ā1.14) | 0.006 |
Grade | ||||||||
āLow | 1/3 | 168 | 1.00 | (Ref) | ā | 1.00 | (Ref) | ā |
āHigh | 15/22 | 1315 | 2.29 | (0.30ā17.52) | 0.3 | 12.33 | (0.42ā28.97) | 0.03 |
Telomere lengths | ||||||||
āNormal | 6/10 | 417 | 1.00 | (Ref) | ā | 1.00 | (Ref) | ā |
āShort | 1/13 | 801 | 0.13 | (0.02ā1.12) | 0.06 | 0.03 | (0.01ā0.29) | 0.003 |
āALT | 9/2 | 264 | 1.93 | (0.68ā5.49) | 0.2 | 1.21 | (0.41ā3.59) | 0.7 |