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Table 3 Association of telomere lengths with overall survival in patients with NF1-associated MPNST

From: Telomere alterations in neurofibromatosis type 1-associated solid tumors

Ā 

Univariate

Multivariate

Ā 

Death/Censor

Person-time (months)

HR

(95% CI)

P-value

HR

(95% CI)

P-value

Age

16/25

1482

1.01

(0.98ā€“1.04)

0.5

1.08

(1.02ā€“1.14)

0.006

Grade

ā€ƒLow

1/3

168

1.00

(Ref)

ā€“

1.00

(Ref)

ā€“

ā€ƒHigh

15/22

1315

2.29

(0.30ā€“17.52)

0.3

12.33

(0.42ā€“28.97)

0.03

Telomere lengths

ā€ƒNormal

6/10

417

1.00

(Ref)

ā€“

1.00

(Ref)

ā€“

ā€ƒShort

1/13

801

0.13

(0.02ā€“1.12)

0.06

0.03

(0.01ā€“0.29)

0.003

ā€ƒALT

9/2

264

1.93

(0.68ā€“5.49)

0.2

1.21

(0.41ā€“3.59)

0.7