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Table 3 Association of telomere lengths with overall survival in patients with NF1-associated MPNST

From: Telomere alterations in neurofibromatosis type 1-associated solid tumors

  Univariate Multivariate
  Death/Censor Person-time (months) HR (95% CI) P-value HR (95% CI) P-value
Age 16/25 1482 1.01 (0.98–1.04) 0.5 1.08 (1.02–1.14) 0.006
Grade
 Low 1/3 168 1.00 (Ref) 1.00 (Ref)
 High 15/22 1315 2.29 (0.30–17.52) 0.3 12.33 (0.42–28.97) 0.03
Telomere lengths
 Normal 6/10 417 1.00 (Ref) 1.00 (Ref)
 Short 1/13 801 0.13 (0.02–1.12) 0.06 0.03 (0.01–0.29) 0.003
 ALT 9/2 264 1.93 (0.68–5.49) 0.2 1.21 (0.41–3.59) 0.7