Table 2 Association of ALT status with overall survival in patients with glioma
From: Telomere alterations in neurofibromatosis type 1-associated solid tumors
Univariate | Multivariate | |||||||
|---|---|---|---|---|---|---|---|---|
Death/Censor | Person-time (months) | HR | (95% CI) | P-value | HR | (95% CI) | P-value | |
Age | 18/30 | 3469 | 1.05 | (1.02–1.08) | 0.001 | 1.02 | (0.98–1.05) | 0.3 |
Grade | ||||||||
Low | 6/25 | 2762 | 1.00 | (Ref) | – | 1.00 | (Ref) | – |
High | 12/5 | 707 | 6.69 | (2.30–19.41) | 0.0005 | 3.36 | (0.94–12.10) | 0.06 |
ALT status | ||||||||
Negative | 10/26 | 3221 | 1.00 | (Ref) | – | 1.00 | (Ref) | – |
Positive | 8/4 | 248 | 7.86 | (2.68–23.06) | 0.0002 | 3.62 | (1.17–11.17) | 0.03 |