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Table 2 Association of ALT status with overall survival in patients with glioma

From: Telomere alterations in neurofibromatosis type 1-associated solid tumors

  Univariate Multivariate
  Death/Censor Person-time (months) HR (95% CI) P-value HR (95% CI) P-value
Age 18/30 3469 1.05 (1.02–1.08) 0.001 1.02 (0.98–1.05) 0.3
Grade
 Low 6/25 2762 1.00 (Ref) 1.00 (Ref)
 High 12/5 707 6.69 (2.30–19.41) 0.0005 3.36 (0.94–12.10) 0.06
ALT status
 Negative 10/26 3221 1.00 (Ref) 1.00 (Ref)
 Positive 8/4 248 7.86 (2.68–23.06) 0.0002 3.62 (1.17–11.17) 0.03