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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Aβ43 in human Alzheimer’s disease: effects of active Aβ42 immunization

Fig. 4

Aβ peptides in the cerebrovasculature of AD cases. Analysis of the numbers of parenchymal (a) and leptomeningeal (b) vessels affected by Aβ43, Aβ42, and Aβ40 in AD cases shows significantly lower numbers of vessels affected by Aβ43 compared to the other peptides. Images of cerebrovascular immunostaining of Aβ43 (c), Aβ42 (d), and Aβ40 (e) in the same cortical area of an AD case. Box plots show median values with the 25th and 75th percentile as boundaries and whiskers indicating minimum and maximum values. Scale bar = 50 μm. *p ≤ 0.05; **p ≤ 0.01

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