Fig. 4

Functional interaction networks of the differentially expressed genes (DEGs) only identified either the acute or the chronic in vivo neurovascular units (NVUs). a The functional interaction network analysis using the DEGs only identified in the acute in vivo NVUs showed that PLK1 and CCNB1 are highly connected (with more than 50 edges) and 36 others DEGs with 31–50 edges. b The network analysis using the DEGs only identified in chronic in vivo NVUs showed that JUN, FOS, MAPK1 were highly connected (with more than 50 edges), and 14 others DEGs with 31–50 edges. The human homologous genes corresponding to the DEGs identified in each mouse models were used for the network analysis