Skip to main content

Table 1 β-amyloid and tau lesions in mouse lemurs of the Alzheimer- (AD) and control-inoculated (CTRL) groups. β-amyloid plaques or β-amyloid angiopathy (CAA) were detected only in Alzheimer-inoculated animals. Tau lesions detected in two Alzheimer-inoculated animals (AT8, MC1 and AT100 antibodies). * correspond to two animals that were euthanized at 12 months post inoculation. AD1 displayed β-amyloid angiopathy, high Aβ1–40 and low Aβ1–42 levels. AD2 did not display angiopathy and had low Aβ1–40 and high Aβ1–42 levels

From: Encephalopathy induced by Alzheimer brain inoculation in a non-human primate

Group Animal β-Amyloid Tau - AT8 Tau - MC1 Tau - AT100
AD2 265B + (plaques) ++ ++ ++
AD2 260B + (plaques) ++ ++ ++
AD1 169ABC ± (plaques) 0 0 0
AD2 190IAB ± (plaques) 0 0 0
AD1 211DBA ± (CAA) 0 0 0
CTRL 189CBD 0 0 0 0
CTRL 190IC 0 0 0 0
CTRL 169ABB 0 0 0 0
CTRL 259BB* 0 0 0 0
CTRL 213ABA* 0 0 0 0