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Table 2 Pathological characteristics of subject population

From: A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

  PD PDD Total p value
Lewy bodies
 Group size 12 21 33  
 Neocortical 3 (25%) 18 (86%) 21 (64%)  
 Limbic 3 (35%) 0 (0%) 3 (9%)  
 Brainstem 6 (50%) 3 (14%) 9 (27%) 0.001a
Group size* 11 20 31  
 Braak 0 0 (0%) 2 (10%) 2 (6%)  
 Braak 1 3 (27%) 5 (25%) 8 (26%)  
 Braak 2 3 (27%) 2 (10%) 5 (16%)  
 Braak 3 3 (27%) 6 (30%) 9 (29%)  
 Braak 4 2 (18%) 5 (25%) 7 (23%)  
 Braak 5 0 (0%) 0 (0%) 0 (0%)  
 Braak 6 0 (0%) 0 (0%) 0 (0%) 0.86a
CERAD
 Group size* 12 20 32  
 None 1 (8%) 8 (40%) 9 (28%)  
 Sparse 11 (92%) 12 (60%) 23 (72%) 0.10b
  1. aChi-squared test
  2. bFisher’s exact test
  3. *Data for one or more patient was unavailable