Table 2 Pathological characteristics of subject population
From: A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease
PD | PDD | Total | p value | |
|---|---|---|---|---|
Lewy bodies | ||||
Group size | 12 | 21 | 33 | |
Neocortical | 3 (25%) | 18 (86%) | 21 (64%) | |
Limbic | 3 (35%) | 0 (0%) | 3 (9%) | |
Brainstem | 6 (50%) | 3 (14%) | 9 (27%) | 0.001a |
Group size* | 11 | 20 | 31 | |
Braak 0 | 0 (0%) | 2 (10%) | 2 (6%) | |
Braak 1 | 3 (27%) | 5 (25%) | 8 (26%) | |
Braak 2 | 3 (27%) | 2 (10%) | 5 (16%) | |
Braak 3 | 3 (27%) | 6 (30%) | 9 (29%) | |
Braak 4 | 2 (18%) | 5 (25%) | 7 (23%) | |
Braak 5 | 0 (0%) | 0 (0%) | 0 (0%) | |
Braak 6 | 0 (0%) | 0 (0%) | 0 (0%) | 0.86a |
CERAD | ||||
Group size* | 12 | 20 | 32 | |
None | 1 (8%) | 8 (40%) | 9 (28%) | |
Sparse | 11 (92%) | 12 (60%) | 23 (72%) | 0.10b |