
MannWhitney^{a}

ttest^{b}

Multiple linear regression^{c}


Δtau314

p = 0.027

p = 0.041

p = 0.082

Ttau

p = 0.00055

p = 0.0031

p = 0.038

Δtau314:Ttau

p = 0.0013

p = 0.00064

p = 0.0041

GAPDH

p = 0.15

p = 0.29

p = 0.29

Casp2:GAPDH

p = 0.0036

p = 0.0035

p = 0.0070

 ^{a}The twotailed, unpaired MannWhitney test was performed
 ^{b}The twotailed, unpaired ttest with Welch’s correction was performed on the log transformed outcomes
 ^{c}Multiple linear regression was used to analyze the log transformed outcomes of protein levels with adjustment for age at death, sex and PMI of brain tissue harvest