Fig. 1
From: Chronic traumatic encephalopathy in two former Australian National Rugby League players
Phosphorylated Tau immunohistochemistry (a-e) and haematoxylin and eosin staining (f) in Case1 (a-c) and Case2 (d-f). (a) pTAu staining is irregularly distributed at the sulcal depths in both neurons and glia. (b) high power view of boxed area in (a) showing perivascular accentuation of pTau staining. (c) prominent proximal dendrite staining with pTau in CA4 neurons in Case1. (d) perivascular pTAu staining in sulcal depths of Case2 (frontal cortex). (e) high power view of boxed area in (d). (f) globose fibrillary tangles in the substantia nigra with some pigment incontinence and gliosis in Case2