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Table 1 Summary of available clinical, histologic, and molecular data from each astrocytoma subgroup analyzed

From: Total copy number variation as a prognostic factor in adult astrocytoma subtypes

Group Tumor Type n Age at Onset (years) Median Progression-Free Survival (months) Median Overall Survival (months) Histologic Grade (II/III/IV) CNV Level (%) Cases with Chromothripsis Mutation Count Instability Gene Mutations
1 IDH-mut LGG 24 38.8 ± 1.9 95 > 172 12/12/0 9.1 ± 1.6 2 (8.3%) 43 ± 10.5 1 (4.1%)
2 IDH-mut CDK4/          
CDKN2A/B LGG 22 38.8 ± 1.9 32 36 4/18/0 21.3 ± 2.5 6 (27.3%) 33.3 ± 1.3 7 (31.8%)
3 IDH-mut GBM 22 40.5 ± 2.7 10 33 0/0/22 20 ± 2.7 9 (40.9%) 67.4 ± 2.75 8 (36.4%)
4 IDH-wt LGG 25 54.0 ± 2.6 10.5 15.5 0/25/0 19.9 ± 1.8 5 (20.0%) 64.9 ± 16.7 5 (20.0%)
5 IDH-wt GBM 42 62.8 ± 1.7 6 13 0/0/42 22.2 ± 1.6 11 (26.2%) 57.0 ± 2.5 10 (23.8%)