Fig. 3
From: Total copy number variation as a prognostic factor in adult astrocytoma subtypes
Total copy number variation averages demonstrating a significant difference between IDH-mutant LGGs without CDK4 amplification or CDKN2A/B deletion and both IDH-mutant LGGs with CDK4 or CDKN2A/B alterations (p = 0.0003) and IDH-mutant GBMs (p = 0.0078), but not between IDH-mutant LGGs with CDK4 or CDKN2A/B alterations and IDH-mutant GBMs (p = 0.7783) (a); no significant difference was found in total mutation burden between any group of IDH-mutant astrocytoma (b). There was no significant difference between IDH-wildtype LGGs and IDH-wildtype GBMs in terms of overall copy number variation (p = 0.3732) (c) or total mutation burden (p = 0.5627) (d)