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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Total copy number variation as a prognostic factor in adult astrocytoma subtypes

Fig. 1

Kaplan-Meier survival curves demonstrating a significant difference between IDH-mutant LGGs without CDK4 amplification or CDKN2A/B deletion and both IDH-mutant LGGs with CDK4 or CDKN2A/B alterations (p = 0.0224) and IDH-mutant GBMs (p = 0.0032), but not between IDH-mutant LGGs with CDK4 or CDKN2A/B alterations and IDH-mutant GBMs (p = 0.0769) in terms of progression-free survival (a). There was also a significant difference between IDH-mutant LGGs and both IDH-mutant LGGs with CDK4 or CDKN2A/B alterations (p = 0.0150) and IDH-mutant GBMs (p = 0.0081), but not between IDH-mutant LGGs with CDK4 or CDKN2A/B alterations and IDH-mutant GBMs (p = 0.2892) in terms of overall survival (b). No significant differences are identified between IDH-wildtype LGGs and IDH-wildtype GBMs in terms of progression-free survival (p = 0.2050) (c) or overall survival (p = 0.9351) (d)

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