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Table 1 Gene Ontology (GO) results of the hyper-methylated sites

From: Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma

ID Description Number of genes (intersection/ total) Significance (p-value, FDR)
GO:0008283 The multiplication or reproduction of cells, resulting in the expansion of a cell population. 50 / 263 0, 0
GO:0016338 The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction. 6 / 13 0, 0
GO:0071364 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus. 12 / 33 0.004, 0.019
  1. ID: GO ID, Description: GO Term description, Number of genes: “total” is the number of genes that are mapped in the 450 K bead array in the GO term, “intersection” means the number of genes that have associations with the selected hyper-methylated sites among the total, Significance: “p-value” was obtained from permutation test, “FDR” is False Discovery Rate (see materials and methods)