Table 1 Antibody Characteristics
Target | Clone | Raised in | Poly v. Mono | Company | Dilution | Pretreatment | Brain regions |
|---|---|---|---|---|---|---|---|
β-amyloid | 6E10 | Mouse | Mono | Covance | 1:2500 | ER2 (20 min) | MFG, MTG, STG, IPL, OCX, striatum, hippocampus, MB, CBL |
PHF-tau | AT8 | Mouse | Mono | Pierce | 1:1000 | ER 1 (10 min) | MFG, MTG, STG, IPL, OCX, hippocampus, |
α-synuclein | LB509 | Mouse | Mono | Invitrogen | 1:250 | ENZ1 (10 min) | MFG, IPL, amygdala, MB |
pTDP-43 | ID3 | Rat | Mono | Millipore | 1:1000 | ER 1 (10 min) | MFG, MTG, STG, amygdala, hippocampus |
Synaptophysin | MRQ-40 | Rabbit | Mono | Novus Biologicals | 1:100 | ER 2 (20 min) | MFG, MTG, STG, OCX, hippocampus |