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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Fig. 7

Quantitative pathology for pTau and pTDP-43 in the resilient group: a The resilient group had less quantitative pTau burden in the MFG. b Quantitative assessments of pTDP-43 also revealed less pathologic burden in TEC, EC, and HPC in the resilient group compared to AD dementia matches. Amygdala showed a trend for reduced TDP-43 immunoreactivity (p = 0.0630). (MFG, middle frontal gyrus; MTG, middle temporal gyrus; STG, superior temporal gyrus; MTC, mesial temporal cortex; EC, entorhinal cortex; HPC, hippocampus; TEC, transentorhinal cortex; AMY, amygdala) *p < 0.05; Wilcoxon matched-pairs signed-ranks test

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