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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Transcriptome and proteome profiling of neural stem cells from the human subventricular zone in Parkinson’s disease

Fig. 4

Proteomics analysis reveals differential protein expression in CD271+ NSCs of PD patients. a Schematic of experimental set-up. b Vulcano plot showing differentially expressed proteins in CD271+ NSCs of PD patients (red = downregulated; green = upregulated) (p-value < 0.05; logFC > 0.1). c Panther pathway analysis showing changes in signaling pathways involved in metabolism and PD (p-value < 0.05). d GO analysis (biological process) further highlights dysregulation of metabolic processes. e Protein-protein interaction (PPI) analysis showing the top 10 proteins to interact with downregulated proteins

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